Clone：

KEL-CD3-001

Regulatory Status：

RUO

Workshop：

V CD03.05

Other Names：

T3, CD3ε

Isotype

human IgG1, κ

Description

CD3ε is a 20 kD chain of the CD3/T-cell receptor   (TCR) complex which is composed of two CD3ε , one CD3γ , one CD3δ, one CD3ζ (CD247), and a T-cell receptor (α/β or γ/δ)   heterodimer. It is found on all mature T lymphocytes, NK-T cells, and some   thymocytes. CD3, also known as T3, is a member of the immunoglobulin   superfamily that plays a role in antigen recognition, signal transduction,   and T cell activation.

Isotype Control：

PerCP/Cyanine5.5 human IgG1, κ

Verified Reactivity：

Human

Antibody Type：

Recombinant Antibody

Host Species：

Mouse

Formulation：

Phosphate-buffered solution, pH 7.2, containing   0.09% sodium azide and BSA (origin USA)

Preparation：

The antibody was purified by affinity   chromatography, and conjugated with PerCP/Cyanine5.5 under optimal   conditions.

Storage & Handling：

The antibody solution should be stored undiluted   between 2°C and 8°C, and   protected from prolonged exposure to light. Do not freeze.

Application：

FC - Quality tested

Recommended Usage：

Each lot of this antibody is quality control tested   by immunofluorescent staining with flow cytometric analysis. For flow   cytometric staining, the suggested use of this reagent is 5 µl per million   cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. *   PerCP/Cyanine5.5 has a

maximum absorption of 482 nm and 564 nm and a   maximun emission of 690 nm.

Excitation Laser：

Blue Laser (488 nm)

Ligand/Receptor：

Antigen recognition, signal transduction, T cell   activation， Peptide antigen bound to MHC

Cell Type：

NKT cells, T cells, Thymocytes, Tregs

Biology Area：

Immunology

Molecular Family：

CD Molecules, TCRs

Antigen References：

1. Barclay N, et al. 1993. The Leucocyte FactsBook.   Academic Press. San Diego.

2. Beverly P, et al. 1981. Eur. J. Immunol. 11:329.

3. Lanier L, et al. 1986. J. Immunol.   137:2501-2507.

Gene ID：

916